化学化工学院教授、博士、硕导

邮箱：puzhang@swu.edu.cn

教育经历

2013年-2018年 西南大学化学化工学院，分析化学，硕博连读。

研究及工作经历

2018年-2021年 在以色列耶路撒冷希伯来大学化学系，博士后。

2022年-至今   西南大学化学化工学院，特聘教授

研究方向

DNA纳米技术和新型核酸功能纳米材料，利用发光、电化学分析平台，实现针对miRNA的传感、细胞成像及药物释放的诊疗一体化。

科研项目

主持国家自然科学基金、省部级自然科学基金共4项。

近期代表性论著（不超过十项）

1. Z. Yang, J. Zhou, F. Liu, Y. Chai, P. Zhang,* and Ruo Yuan*. CsPbBr₃ Perovskite Quantum Dots Encapsulated by a Polymer Matrix for Ultrasensitive Dynamic Imaging of Intracellular MicroRNA. Anal. Chem., 2024, 96, 10738-10747.

2. S. Bu, Li Song, Y. Ding, Y. Yang, Y. Liang, Y. Chai, P. Zhang,* Y. Fu,* R. Yuan*. Dual-Ligand Ruthenium Coordination Polymer-Derived SelfEnhanced Electrochemiluminescent Emitters for Sensitive Detection of Procalcitonin. Anal. Chem., 2024, 96, 10809-10816.

3. Y. Ouyang,‡ P. Zhang,‡ I. Willner. DNA Tetrahedra as Functional Nanostructures: From Basic Principles to Applications. Angew. Chem. Int. Ed., 2024, e202411118. (first co-author)

4. R. Meng , X. Zhang , J. Liu, Y. Zhou, P. Zhang,* Yaqin Chai,* Ruo Yuan.* Dual-layer 3D DNA nanostructure: The next generation of ultrafast DNA nanomachine for microRNA sensing and intracellular imaging. Biosens. Bioelectron., 2023, 237, 115517.

5. P. Zhang,‡ Y. Ouyang,‡ Y. Zhuo, Y. Chai, R. Yuan,* Recent Advances in DNA Nanostructures Applied in Sensing Interfaces and Cellular Imaging. Anal. Chem., 2023, 95, 407-419.

6. P. Zhang, Y. Zhuo, Y. Chai, R. Yuan.* Structural DNA tetrahedra and its electrochemical-related surface sensing. Trends in Anal. Chem., 2023, 160, 116979.

7. P. Zhang, J. Jiang, R. Yuan,* Y. Zhuo,* Y. Chai.* Highly Ordered And Field-Free 3D DNA Nanostructure: The Next Generation of DNA Nanomachine for Rapid Single-Step Sensing. J. Am. Chem. Soc., 2018, 140, 9361-9364.

8. P. Zhang, Y. Ouyang, Y. S. Sohn, M. Fadeev, O. Karmi, R. Nechushtai, I. Stein, E. Pikarsky, I. Willner.* miRNA-Guided Imaging and Photodynamic Therapy Treatment of Cancer Cells Using Zn (II)-Protoporphyrin IX-Loaded Metal-Organic Framework Nanoparticles. ACS nano, 2022, 16, 1791-1801.

9. P. Zhang, Y. Ouyang, Y. S. Sohn, R. Nechushtai, E. Pikarsky, C. Fan, I. Willner.* pH-And miRNA-Responsive DNA-Tetrahedra/Metal-Organic Framework Conjugates: Functional Sense-And-Treat Carriers. ACS Nano, 2021, 15, 6645-6657.

10. P. Zhang, L. Yue, M. Vazquez-Gonzalez, Z. Zhou, W.-H. Chen, Y. S. Sohn, R. Nechushtai, I. Willner.* MicroRNA-Guided Selective Release of Loads from Micro-/Nanocarriers Using Auxiliary Constitutional Dynamic Networks. ACS Nano, 2020, 14, 1482-1491.