其他成员(姓氏笔画为序)
肖波 教授
发布时间: 2025-05-30 11:03 作者: 来源: 浏览次数:

西塔学院教授、博士、

邮箱:bxiao@swu.edu.cn

教育经历

2002.092006.07 本科   西南大学  生物工程系

2006.092008.07  硕士 华中科技大学 生物医学工程系

2008.092011.07  博士 华中科技大学  生物医学工程系

研究及工作经历

2011.092014.09   美国乔治亚州立大学生物医学科学研究院 博士后  

2014.092017.06   西南大学洁净能源与先进材料研究院 副教授  

2017.07 至今      西南大学 研究员

研究方向

口服纳米医学:基于植物(如桑叶、茶叶等)、蚕丝蛋白(丝素、丝胶等)和合成高分子的药用功能和特殊理、化性能,我们试图利用其作为天然纳米药物或药物(如siRNApDNA、化学药物等)的载体材料,设计并构建各种新型纳米粒子、微米粒子、水凝胶或纤维等载药系统,用于多种炎症性疾病和肿瘤的诊断、预防和治疗

科研项目

先后主持国家高层次人才项目、国家自然科学基金(3项)、重庆市自然科学基金和美国心脏协会基金等项目。

近期代表性论著(不超过十项)

1. Ya Ma, Lian Duan, Jianfeng Sun, Shuangquan Gou, Fengyuan Chen, Yuqi Liang, Fangyin Dai, Bo Xiao*. Oral nanotherapeutics based on Antheraea pernyi silk fibroin for synergistic treatment of ulcerative colitis. Biomaterials 2022;282: 21410.IF = 12.4

2. Shuangquan Gou, Nanxi Chen, Xiaoai Wu, Menghang Zu, Shixiong Yi, Binwu Ying*, Fangyin Dai, Bowen Ke*, Bo Xiao*. Multi-responsive nanotheranostics with enhanced tumor penetration and oxygen self-producing capacities for multimodal synergistic cancer therapy. Acta Pharm. Sin. B 2022;12(1):406-423. (IF = 11.4

3. Chen Q., Li Q., Liang Y., Zu M., Chen N., Canup B., Luo L., Wang C.*, Zeng L.*, and Xiao B.* Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation. Acta Pharm. Sin. B 2022;12(2):907-923.   (IF = 11.4

4. Menghang Zu, Dengchao Xie, Brandon S.B. Canup, Nanxi Chen, Yajun Wang, Ruxin Sun, Zhan Zhang, Yuming Fu,* Fangyin Dai,* and Bo Xiao*. ‘Green’ nanotherapeutics from tea leaves for orally targeted prevention and alleviation of colon diseases. Biomaterials 2021; 279: 121178. IF = 12.4

5. Zu M., Ma Y., Cannup B., Xie D., Jung Y., Zhang J., Yang C., Gao F.*, Merlin D.*, and Xiao B.*. Oral delivery of natural active small molecules by polymeric nanoparticles for the treatment of inflammatory bowel diseases. Adv. Drug Deliv. Rev. 2021;176:113887. (IF = 15.4

6. Zhang X., Huang Y., Song H., Canup B.S.B., Gou S., She Z., Dai F.*, Ke B.*, and Xiao B.*. Inhibition of growth and lung metastasis of breast cancer by tumor-homing triple-bioresponsive nanotherapeutics. Journal of Controlled Release 2020;328:454-469. IF = 9.7

7. Gou S., Yang J., Ma Y., Zhang X., Zu M., Kang T., Liu S., Ke B.*, and Xiao B.*. Multi-responsive nanococktails with programmable targeting capacity for imaging-guided mitochondrial phototherapy combined with chemotherapy. Journal of Controlled Release 2020;327: 371-383. IF = 9.7

8. Gou S., Huang Y., Wan Y., Ma Y., Zhou X., Tong X., Huang J.*, Kang Y.*, Pan G., Dai F., and Xiao B.*. Multi-bioresponsive silk fibroin-based nanoparticles with on-demand cytoplasmic drug release capacity for CD44-targeted alleviation of ulcerative colitis. Biomaterials 2019; 212:39-54. IF = 12.4