化学化工学院教授、博士、博导

邮箱：yqchai@swu.edu.cn

教育经历

2004年毕业于西南大学并获得博士学位

研究及工作经历

1999至2000年在香港城市大学做访问学者

1999年10月于西南大学化学化工学院工作，任西南大学化学化工学院教授、博士生导师

研究方向

1.开展电化学及光致电化学生物分析策略研究

2.结合分子识别（免疫、适体及DNA、MicroRNA及细胞）及多种信号放大策略，构建生物传感器用于疾病标志物及肿瘤细胞检测评估研究。

3.电化学及光致电化学分析生物成像分析研究

科研项目

1.国家自然科学基金面上项目：钌配合物功能化聚乙烯亚胺电致化学发光材料的制备及其在免疫传感器中的应用，2015.01-2018.12

2.重庆市自然科学基金重点项目：基于功能化纳米材料的重金属离子电化学传感器构建及其在环境分析中的应用，2011.04-20.14.3

近期代表性论著（不超过十项）

1. Zhang, Pu; Jiang, Jie; Yuan, Ruo*; Zhuo, Ying*; Chai, Yaqin*. Highly ordered and field-free 3D DNA nanostructure: the next generation of DNA nanomachine for rapid single-step sensing. J. Am. Chem. Soc., 2018, 140, 9361

2. Kou, Beibei; Chai, Yaqin*; Yuan, Yali*; Yuan, Ruo*. A DNA nanopillar as a scaffold to regulate the ratio and distance of mimic enzymes for an efficient cascade catalytic platform. Chem. Sci., 2021, 12, 407

3. Zhang, Xiaolong; Yang, Zhehan; Chang, Yuanyuan; Liu, Di; Li, Yunrui; Chai, Yaqin*; Zhuo, Ying*; Yuan, Ruo*. Programmable mismatch-fueled high-efficiency DNA signal converter. Chem. Sci., 2020, 11, 148

4. Liu, Jiali; Zhang, Jiaqi; Tang, Zhiling; Zhuo, Ying; Chai, Yaqin*; Yuan, Ruo*. Near-infrared aggregation-induced enhanced electrochemiluminescence from tetraphenylethylene nanocrystals: a new generation of ECL emitters. Chem. Sci., 2019, 10, 4497

5. Chen, Anyi; Liang, Wenbin; Wang, Haijun; Zhuo, Ying; Chai, Yaqin*; Yuan, Ruo*. Anodic electrochemiluminescence of carbon dots promoted by nitrogen doping and application to rapid cancer cell detection. Anal. Chem., 2020, 92, 1379

6. Li, Yunrui; Chang, Yuanyuan; Ma, Jing; Wu, Zhongyu; Yuan, Ruo*; Chai, Yaqin*. Programming a target-initiated bifunctional DNAzyme nanodevice for sensitive ratiometric electrochemical biosensing. Anal. Chem., 2019, 91, 6127

7. Xia, Lingying; Li, Mengjie; Wang, Hai-Jun; Yuan, Ruo*; Chai Ya-Qin*. Novel single-enzyme-assisted dual recycle amplification strategy for sensitive photoelectrochemical microRNA assay. Anal. Chem. 2020, 92, 14550

8. Yang, Rong; Liu, Jiali; Chai, Yaqin*; Yuan, Ruo*. MnOx MFs as a coreaction accelerator for the construction of a novel ternary electrochemiluminescence system: ultrasensitive detection of microRNA.Chem. Commun., 2020, 56, 976

9. Kou, Beibei; Yuan, Yali; Yuan, Ruo*; Chai, Yaqin*. Electrochemical biomolecule detection based on the regeneration of high-efficiency cascade catalysis for bifunctional nanozymes. Chem. Commun., 2020, 56, 2276

10. Xu, Sai; Chang, Yuanyuan; Wu, Zhongyu; Li, Yunrui; Yuan, Ruo*, Chai, Yaqin*. One DNA circle capture probe with multiple target recognition domains for simultaneous electrochemical detection of miRNA-21 and miRNA-155. Biosens. Bioelectron., 2019, 149, 111848

国家专利